Phage Complete
Frequently Asked Questions
Lipopolysaccharides (LPS) released from dying gram-negative bacteria (such as e.Coli) can trigger the body to release low levels of histamine. This should last about as long as die-off does, which varies from person to person, but generally 3-7 days. Just keep in mind that killing unwanted bacteria and making room for beneficial bacteria is a good thing. Since Phage Complete kills gram-negative bacteria this can temporarily cause histamine symptoms.
“The effect of bacterial lipopolysaccharide (LPS) on histamine release from human basophils. I. Enhancement of immunologic release by LPS… lipopolysaccharide (LPS)… enhanced by an average of sixfold the response of peripheral blood basophils obtained from allergic donors to several allergens in vitro as judged by release of histamine.” — https://www.ncbi.nlm.nih.gov/pubmed/2578909
“The potentiating effect of LPS was observed in grass pollen and dog dander allergic patients as well as in patients sensitized to E. coli or Staph, aureus bacteria… Bacteria can release histamine by immunological or nonimmunological mechanisms, and only the immunological histamine release was found to be potentiated by LPS. It is speculated that endotoxins reinforce release of histamine caused by allergens in allergic patients or by bacteria in persons sensitized to these microorganisms.” — http://onlinelibrary.wiley.com/doi/10.1111/j.1398-9995.1986.tb00288.x/abstract
So getting rid of this LPS producing bacteria is important as it produces (sheds) LPS molecules 24/7; again, killing unwanted bacteria and making room for beneficial bacteria is a good thing. LPS producing bacteria might actually be one of the reasons some people suffer from histamine symptoms even when not consuming any histamine containing / liberating foods.
Taking an antihistamine, such as Zyrtec, can help with symptom relief. There is also some evidence that it works as a mast cell stabilizer, to block the histamine (your body would release) from being release in the first place. Worth a try.
Following the FAQ advice for die-off and cutting back might help.
https://www.theguthealthprotocol.com/wp/phage-complete-faq/?Display_FAQ=1128
These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease. |
These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease. |
All images posted by John Herron are either "Copyrighted John Herron", or are copyrighted by someone else and are used under license. So please don’t use them elsewhere, you’ll get in trouble.
Yes & No.
Because of the probiotic amplifying effect, you need to make sure you are taking probiotic strains that do not encourage histamine production, created d-lactic acid, or interfere with bile acid. Especially those with a high CFU count.
Phage Complete contains only probiotic strains that do not produce these harmful or unwanted side effects and, for most people, should be the only probiotic you need.
SBO / HSO probiotic strains are usually safe to take with phages, but you should take the minimum recommended dosage.
As new research comes out, and is tested by members, I will probably be advising what specific probiotic strains work particularly well with Phage Complete for specific purposes.
The following probiotic bacterial strains should be avoided (really even if you aren’t taking Phage Complete).
Histamine Liberators / Producers:
- Lactobacillus bulgaricus
- Lactobacillus casei
- Lactobacillus delbrueckii
People with histamine intolerance should always avoid these strains, regardless of whether take phages or not.
D-Lactate (D-Lactic Acid) Producing Strains:
- Lactobacillus acidophilus (yes, found in yogurt!)
- Lactobacillus bulgaricus (also very common in yogurt)
- Lactobacillus lactis (found in buttermilk)
- Lactobacillus buchneri
- Lactobacillus delbrueckii subsp. delbrueckii
- Lactobacillus delbrueckii subsp. lactis
- Lactobacillus delbrueckii subsp. bulgaricus,
- Lactobacillus jensenii
- Lactobacillus vitulinus
A couple of these strains are found in lower amounts in Kefir. Kefir contains a lot of different strains, this actually helps lower the risk of D-Lactate from these problematic strains. It is when a strain is taken at a higher CFU count in isolation that you see the most problems. Never the less, you should consume no more than 4 to 6 ounces of kefir per day while taking phages. Also watch for symptoms D-Lactate.
These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease. |
These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease. |
All images posted by John Herron are either "Copyrighted John Herron", or are copyrighted by someone else and are used under license. So please don’t use them elsewhere, you’ll get in trouble.
These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease. |
All images posted by John Herron are either "Copyrighted John Herron", or are copyrighted by someone else and are used under license. So please don’t use them elsewhere, you’ll get in trouble.